Acta Chemica Malaysia

Journal: Acta Chemica Malaysia (ACMY)
Author: Chinyere Benardette Chinaka Ikpa, Chinomnso U. Ikpa, Gladys C. Ezeh, Samuel Okwudili Onoja
ISSN: 2576-6732
e-ISSN: 2576-6724

This is an open access journal distributed under the Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.2478/acmy-2021-0011

Laminaria saccharina is an aquatic plant mainly used as dietary fibre in Europe, America and Japan. This study investigated the phytochemical composition and antibacterial properties of the chloroform extract of Laminaria saccharina leaves. The phytochemical composition and antibacterial properties of the leaves were evaluated using standard methods. The chloroform fraction of the leaves extract was used for antibacterial screening. The chloroform fraction was fractionated and the pure compound isolated was characterized using infrared (IR), nuclear magnetic resonance (NMR) and mass spectrometer. The phytochemical result showed the presence of alkaloid 2.5 ± 0.20%, phenol 0.38 ± 0.22%, flavonoids 3.60 ± 0.20%, saponins 1.00 ± 0.20% and tannins 0.05 ± 0.20% w/w. The functional groups present in IR absorption bands, the signals on the NMR and mass of 477 m/z on mass spectrometer confirmed the characterization and elucidation of a glycosaccharide (compound 1) called 12-ethyl-5,8-dihydroxy-7-(hydroxymethyl) cyclopentaquinoline-2-one-6-methoxyglucopyronose with calculated mass of 473.514 m/z. The extract inhibited the growth of both Gram-positive and Gram-negative bacterial isolates. The minimum inhibitory concentration (MIC) of the extract against Staphylococcus aureus, Escherichia coli, and Proteus mirabilis was 1.25 mg/ml and 2.50 mg/ml against Streptococcus pneumonia. The chloroform fraction of L. saccharina inhibited the growth of both Gram-positive and Gram-negative organism and could be used in the treatment of bacterial infection as a broad-spectrum antibacterial agent.

Journal: Acta Chemica Malaysia (ACMY)
Author: IgeAyodeji Rapheal and Bamisaye Abayomi
ISSN: 2576-6732
e-ISSN: 2576-6724

This is an open access journal distributed under the Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.2478/acmy-2021-0012

The concept of using biomass as an alternative source of energy is justified by its availability, abundance, easy accessibility and its eco-friendly nature. This article presents the production of briquettes from Maize stalk (MS), Neem leaves (NL) and maize stalk and neem leaves (MS-NL) admixture using cassava starch as binder. This study presents the effects of the admixture on the quality of the briquette and its combustibility. The physico-chemical parameters of the briquettes were evaluated. The moisture content of all the briquette samples were less than 20% of the recommended standard value with A (100% MS) having the highest mean value of 9.26±0.09% while E (100% NL) recorded the least mean value of 7.48±0.03% at p < 0.05. The volatile matter content decreases in order of 79.04±0.21%, 77.68±0.02%, 72.23±0.05%, 70.37±0.50%, 68.74±0.15% for A, B (75%MS-25%NL), C (50%MS-50%NL), D (25%MS-75%NL) and E respectively. However, the calorific value increases in the order of A, B, C, D and E. In which E recorded the highest mean calorific value of 29.64±0.08 MJ/Kg. The findings of this study show that MS had a negative effect on the physicochemical property of the admixtures. It can be concluded that briquettes produced from NS and admixture with high percentage of NS will make a better biofuel.

Journal: Acta Chemica Malaysia (ACMY)
Author: Enemose, Edith A., Nworu, Jerome S., Onunkwo Innocent and Morka, Wisdom E.
ISSN: 2576-6732
e-ISSN: 2576-6724

This is an open access journal distributed under the Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.2478/acmy-2021-0010

As part of the current research for more effective antimalarial drug, Cu (II) complex of sulphamethazine with 1,10 phenanthroline was synthesized. The novel complex was characterized by Elemental analysis, FT-IR and electronic spectroscopy. The novel complex is insoluble in water, which is an indication of covalent and non- electrolyte character. The elemental analysis result of the complex correspond with the proposed formula [Cu(SUF)(phen)(SCN)2]. The electronic spectrum of sulfamethazine and 1, 10- phen showed absorption bands at 212 nm (47169 cm^–1) and 306 nm (32679 cm^–1). These bands were assigned to the n – δ* and π – δ* transitions. The infrared bands were seen at 3443 – 3344 cm–1 which were attributed to the presence of 𝜈𝜈 (NH2), 𝜈𝜈(NH) and 𝜈𝜈(OH) vibrations experience bathochromic shift in the metal complex. The parent ligands acted as a bidentate chelating agent showing coordination through the pyridine nitrogen and the nitrogen of the NH moiety in this case.