SPECIFIC AND NON-SPECIFIC PARAMETERS OF ETHANOLIC EXTRACT OF JOMBANG LEAVES (TARAXACUM OFFICINALE F.H. WIGG.)
Journal: Acta Chemica Malaysia (ACMY)
Author:Annisa Farida Muti, Erna Harfiani, Putu Ayu Amanda Giri, Annisa Ayu Wulandari
This is an open access journal distributed under the Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Taraxacum officinale F.H. Wigg., commonly known as Jombang in Indonesia, is one of the 30 medicinal plants processed into Scientific Jamu. Jombang has been used empirically to both prevent and treat liver illness. In order to maintain consistency in quality, safety, and efficacy, Jombang extract must be standardized; as a result, extracts used as raw materials for medicines have constant specific and non-specific parameters and are expected to meet quality requirements to be accepted in healthcare settings. This research intended to analyze the general standard parameters of the 50%-ethanolic extract of Jombang leaves from Tawangmangu, Indonesia. The specific parameters are organoleptic properties, phytochemical composition, water-soluble and ethanol-soluble extract content; while the non-specific parameters consist of water content, ash content, acid-insoluble ash content, heavy metal, and microbial contamination. Both parameters are determined using the method established by the Indonesian Ministry of Health for General Standard Parameters of Extracts. The results indicated that the 50%-ethanolic extract of Jombang leaves had thick extract, dark brown color, distinctive smell, and slightly bitter taste. Alkaloid, saponins, flavonoids, and steroids were found in the extract’s phytochemical screening results. It contained 67.62% of water-soluble extract and 18.83% of ethanol-soluble extract. Mold and yeast contamination were negative (<1.0 x 103 colonies/ g), Pb and Cd levels were undetectable (<0,009 ppm and <0,00011 ppm, respectively), while the water content value was 13.26%, the ash content value was 9.87%, and the acid insoluble ash content value was 0.48%.